Manforce 50mg Tablet

HOW IT WORKS

Sildenafil hinders the cGMP-specific phosphodiesterase type 5 (PDE5), which is accountable for cGMP degradation in the corpus cavernosum located around the penis. So, penile erection during sexual stimulation is caused by improving penile blood flow resulting from the relaxation of penile tubes and corpus cavernosal smooth tissue. So, this reply is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which animates the whole of cGMP in smooth muscle cells. And, cyclic GMP causes smooth muscle relaxation and increases blood flow into the corpus cavernosum. So, the interference of phosphodiesterase type 5 (PDE5) by sildenafil enhances erectile function by increasing cGMP.

Precautions

Caution taking when using in cases with anatomical deformation of penis or conditions that may predispose them to priapism i.e., painful, persistent erection of the penis (e.g., sickle cell anemia, myeloma or leukemia); mild, temporary, dose-related impairment of value separation (blue/green) may happen. So, report to the physician if the subjects are allergic to fresh ingredients or any other drugs.

Food To Avoid

So, If allergic to any food, please consult with the physician.

Pregnancy/Lactation Protocol

Pregnancy Category: B
Please advise with a doctor during pregnancy & lactation.