Penegra also calls as “Blue Pill” or “Man’s Best Friend.” That is because the drug is indicated for the treatment of Erectile Dysfunction or Impotence. So, In this condition, the men cannot achieve the penile erection at the time of sexual intercourse and, therefore, do not have satisfying sex with the partner. And this condition is most prevalent during the middle ages of men, between 40-70 years of age. Almost 50% of the men suffer during this age. Many medical and lifestyle reasons like smoking, kidney failure, liver failure, obesity, diabetes, etc. are the leading cause of impotence in men.

Only in 10% of cases, the reasons are psychological and can treat with a placebo.

Equivalent brands in the USA

There are various equivalent brands of Penegra that are available in the USA and other parts of the world. So, all the equivalent brands are the brands of the generic Viagra. Various other generic Viagra is Malegra, Kamagra, Silagra, Manforce, Cenforce, Vigora. So, all the brands are available in 25, 50, and 100 mg strengths.

Uses of Penegra 25 mg Tablet

Sildenafil Citrate for treating the following medicinal indications:

• Sexual erectile dysfunction in men (primary indication)- In this condition, the penile erection doesn’t happen at the time of sexual intercourse.
• Antidepressant-associated sexual erectile dysfunction- In men, ED is also due to anti-depressant dose.
• So, in this condition, pulmonary arterial hypertension is an increase in blood pressure in the lungs’ arteries.
• Raynaud’s phenomenon- In this syndrome, the arteries’ spasm causes reduced blood flow. That happens mostly in the fingers and toes.
• High-altitude pulmonary edema (Not recommended). So, there is swelling in the lungs on high altitudes 2500 meters above in this condition. But, in this condition, Sildenafil Citrate is not recommended.

Penegra is also not recommending to use women or children under 12 years of age.

Rare but severe side effects include:

• Priapism- (Prolonged and painful erection for more than 4 hours)
• Deafness

In October 2007, USFDA announced the potential warning of sudden hearing loss mentioned on the label.

Interactions:

• Amlodipine
• Carbamazepine
• Dexamethasone
• Imatinib Mesylate
• Isoniazid
• Terazosin
• ACE inhibitors
• Atenolol
• Tamsulosin
• Warfarin

Severe Interactions are with:

• Clarithromycin
• Ketoconazole
• Atazanavir
• Nitroglycerin

How long should Penegra be continued?

Penegra is to use as and when needs when the sexual activity is anticipate. Just take medicine one hour before the sexual activity is expected. However, if you take Penegra daily, then take Penegra as per the doctor’s advice only. And, try to take medicine at the prescribed time irrespective you perform the sexual activity or not. Do not stop the drug in between without consulting your physician. It would be best if you did not overdose on Penegra. If the dose is missed, then take medicine as soon as you remember it. So, the missed dose usually has no harm to the body.

If you are a heart, kidney, or liver patient, then inform your doctor before taking this drug. Penegra does not recommend for use in women and children under 12 years of age.

How Penegra works?

Sildenafil Citrate is a selective Phosphodiesterase 5 enzyme (PDE5) inhibitor. So, this enzyme is responsible for Erectile Dysfunction. Blocking this enzyme selectively increases Cyclic GMP (Guanosine Monophosphate), which releases chemicals like Nitric Oxide. So, the release of NO causes increased blood flow in the penis, thereby causing its erection. And, it is important to note that blood flow to the penis increases only when a man is sexually aroused and even smoothly fades out when no sexual stimulus occurs.

How to take Penegra?

Take Penegra one hour before the anticipated sexual activity. And, If you take a once-daily dosage schedule, then take the drug as per the doctor’s advice and prescription. And, do not take alcohol along with the drug. You can take medicine with or without food.